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Glumetinib
Artikelnummer: TGM-T5414-100mg
Description: Glumetinib (SCC244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM). Target: c-Met/HGFR. Smiles: Cn1cc(cn1)-c1cnc2cnn(c2c1)S(=O)(=O)c1cnc2ccc(cn12)-c1cnn(C)c1. References: Ai J, et al. Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective...
| Schlagworte: | SCC244 |
| Anwendung: | Potent c-Met inhibitor |
| CAS | 1642581-63-2 |
| MW: | 459.48 D |
ab 52,00 €
Glumetinib
Artikelnummer: Cay28952-1
Glumetinib is a potent inhibitor of c-Met (IC50 = 0.42 nM). It is greater than 2,400-fold selective for c-Met over a panel of 312 kinases. Glumetinib (0.001-1 µM) inhibits c-Met phosphorylation in and proliferation of MET-overexpressing EBC-1 lung and MKN45 gastric cancer cells. It inhibits NCI H441 cell motility...
| Schlagworte: | SCC244,... |
| Anwendung: | Potent c-Met inhibitor |
| CAS | 1642581-63-2 |
| MW: | 459.5 D |
ab 49,00 €
