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Tenalisib
Artikelnummer: Cay30949-10
Tenalisib is an inhibitor of PI3Kdelta and PI3Kgamma (IC50s = 24.5 and 33.2 nM, respectively). It is greater than 300- and 120-fold selective for PI3Kdelta and PI3Kgamma, respectively, over PI3Kalpha and PI3Kbeta. Tenalisib (10 µM) induces cell death in L-540, KM-H2, and L-428 Hodgkin lymphoma cells. It induces cell...
| Schlagworte: | RP 6530, 3-(3-fluorophenyl)-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4H-1-benzopyran-4-one |
| Anwendung: | PI3Kdelta and PI3Kgamma inhibitor |
| CAS | 1639417-53-0 |
| MW: | 415.4 D |
ab 103,00 €
Tenalisib
Artikelnummer: TGM-T13119-100mg
Description: Tenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kdelta and PI3Kgamma(IC50 values of 25 and 33 nM, respectively.). Target: PI3K. Smiles: CC[C@H](Nc1ncnc2nc[nH]c12)c1oc2ccccc2c(=O)c1-c1cccc(F)c1. References: Vakkalanka S, et al. RP6530, a dual PI3K delta/gamma inhibitor, potentiates...
| Schlagworte: | RP6530 |
| CAS | 1639417-53-0 |
| MW: | 415.42 D |
ab 35,00 €
