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VU0422288
VU0422288

Artikelnummer: TGM-T29135-100mg

Description: VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobilization assay.VU0422288 can be used to study Rett syndrome (RTT). Target: GluR. Smiles: Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1. References:...
Schlagworte: ML 396, VU 0422288, VU-0422288, ML-396, ML396
Anwendung: Group III metabotropic glutamate receptor positive allosteric modulator
CAS 1630936-95-6
MW: 360.19 D
ab 72,00 €
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ML-396
ML-396

Artikelnummer: Cay29167-1

ML-396 is a positive allosteric modulator of group III metabotropic glutamate receptors (mGluRs) with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively, in calcium mobilization assays. ML-396 potentiates LSP4-2022-induced reductions in paired-pulse field excitatory post synaptic...
Schlagworte: VU0422288, N-[3-chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide
Anwendung: Group III metabotropic glutamate receptor positive allosteric modulator
CAS 1630936-95-6
MW: 360.2 D
ab 44,00 €
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