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Fezolinetant
Artikelnummer: TGM-T15278-100mg
Description: Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes. Target: Neurokinin receptor. Smiles: C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1. References: Fraser GL, et al. The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile...
| Schlagworte: | ESN-364 |
| Anwendung: | Targets tachykinin receptor 3 (TACR3) |
| CAS | 1629229-37-3 |
| MW: | 358.39 D |
ab 72,00 €
Fezolinetant
Artikelnummer: Cay39523-10
Fezolinetant is a neurokinin-3 (NK3) receptor antagonist (IC50 = 20 nM). It decreases plasma levels of luteinizing hormone (LH) in castrated cynomolgus monkeys when administered at a dose of 5 mg/kg. Fezolinetant (10 mg/kg) prevents increases in body weight and food intake but does not affect uterine weight or...
| Schlagworte: | AS 3472693-00, ESN364,... |
| Anwendung: | NK3 receptor antagonist |
| CAS | 1629229-37-3 |
| MW: | 358.4 D |
ab 138,00 €
