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EZM 2302
Artikelnummer: TGM-T5605-100mg
Description: EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM). Target: Histone Methyltransferase. Smiles: CNC[C@@H](O)COc1ccc(Cl)c(c1)-c1nc(N2CC3(C2)CCN(CC3)C(=O)OC)c(C)c(n1)-c1c(C)noc1C. References: Drew AE, et al. Identification of a CARM1 Inhibitor...
| Schlagworte: | GSK3359088 |
| Anwendung: | PRMT4 inhibitor |
| CAS | 1628830-21-6 |
| MW: | 585.09 D |
ab 67,00 €
EZM2302
Artikelnummer: Cay29954-1
EZM2302 is an inhibitor of protein arginine methyltransferase 4 (PRMT4, IC50 = 6 nM). It decreases asymmetric methylation of the PRMT4 substrate PABP1 (IC50 = 0.038 µM) and increases levels of demethylated SmB (EC50 = 0.018 µM) in RPMI-8226 multiple myeloma cells. EZM2302 inhibits proliferation in a panel of 36...
| Schlagworte: | GSK3359088,... |
| Anwendung: | PRMT4 inhibitor |
| CAS | 1628830-21-6 |
| MW: | 585.1 D |
ab 94,00 €
