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VR23
Artikelnummer: Cay19133-5
VR23 is a chloroquine (Cay-14194) derivative that functions as a proteasome inhibitor (IC50s = 1 nM, 50-100 nM, and 3 µM for trypsin-like, chymotrypsin-like, and caspase-like proteasomes, respectively). It also deregulates the activity of cyclin E and other centrosomal proteins, resulting in the induction of...
| Schlagworte: | 7-chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]-quinoline |
| Anwendung: | Proteasome inhibitor |
| CAS | 1624602-30-7 |
| MW: | 477.9 D |
ab 48,00 €
![VR23 [Proteasome Inhibitor]](https://www.biomol.com/media/image/a3/db/0c/AG-CR1-3676-M001_200x200.png "VR23 [Proteasome Inhibitor]")
VR23 [Proteasome Inhibitor]
Artikelnummer: AG-CR1-3676-M001
Synthetic. Chemical. CAS: 1624602-30-7. Formula: C19H16ClN5O6S. MW: 477.9. Synthetic. Potent selective and reversible chloroquine derivative 20S proteasome inhibitor (all proteolytic subunits). Targets the trypsin-like beta2 subunit of the constitutive 20S proteasome (IC50=1nM). Cross-reacts and inhibits the...
| Schlagworte: | 7-Chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]quinoline |
| Anwendung: | Proteasome inhibitor |
| CAS | 1624602-30-7 |
| MW: | 477,9 D |
ab 33,00 €
