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Roflumilast
Artikelnummer: TGM-T1024-100mg
Description: Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit...
| Schlagworte: | BYK 20869, B9302-107, APTA 2217, BY 217 |
| CAS | 162401-32-3 |
| MW: | 403.21 D |
ab 52,00 €
Roflumilast
Artikelnummer: Cay15141-25
Roflumilast is an inhibitor of phosphodiesterase 4 (PDE4, IC50 = 0.8 nM). It is selective for PDE4 over PDE1, -2, -3, and -5 (IC50s = >10, >10, >10, and 8 µM, respectively). Roflumilast inhibits the production of leukotriene B4 (LTB4, Cay-20110) induced by fMLP (Cay-21495) in isolated human neutrophils with an IC50...
| Schlagworte: | B 9302-107, BY 217, BYK 20869, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-benzamide |
| Anwendung: | PDE4 inhibitor |
| CAS | 162401-32-3 |
| MW: | 403.2 D |
ab 33,00 €
