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HTH-01-015
Artikelnummer: Cay19091-1
NUAK1 (also known as AMPK-related kinase 5) and NUAK2 (also known as SNF1/AMPK-related kinase) are members of the AMP-activated protein kinase (AMPK) family of protein kinases that are activated by the liver kinase B1 tumor suppressor kinase. NUAK kinases are thought to have roles in regulating cell adhesion, cancer...
| Schlagworte: | 5,13-dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6... |
| Anwendung: | Selective NUAK1 inhibitor |
| CAS | 1613724-42-7 |
| MW: | 468.6 D |
ab 100,00 €
HTH-01-015
Artikelnummer: TGM-T2374-100mg
Description: HTH-01-015 is a selective NUAK1 inhibitor with an IC50 of 100 nM. Target: AMPK. Smiles: CN1c2cc3ccccc3cc2C(=O)N(C)c2c(C)nc(Nc3cnn(c3)C3CCNCC3)nc12. References: Banerjee S, et al. Biochem J. 2014, 457(1), 215-225.
| CAS | 1613724-42-7 |
| MW: | 468.55 D |
ab 38,00 €
