Zu "1612191-86-2" wurden 2 Artikel gefunden!
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BAR502
Artikelnummer: TGM-TQ0252-100mg
Description: BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 µM and 2 µM). Target: Autophagy, FXR, GPCR19. Smiles: CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCO)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12. References: Festa C, et al. Exploitation of cholane scaffold for the discovery of potent and...
| Anwendung: | GPBAR1 /FXR dual agonist |
| CAS | 1612191-86-2 |
| MW: | 392.62 D |
ab 105,00 €
BAR502
Artikelnummer: Cay22462-1
BAR502 is a dual agonist of the G protein-coupled bile acid-activated receptor and farnesoid x receptor (GP-BAR1 and FXR, EC50s = 0.2 and 1 µM, respectively). It increases the expression of the FXR-regulated bile salt export pump (BSEP), organic solute transporter alpha (OSTalpha), and small heterodimer partner...
| Schlagworte: | (3alpha,5beta,6alpha,7alpha)-6-ethyl-24-norcholane-3,7,23-triol |
| Anwendung: | GPBAR1 /FXR dual agonist |
| CAS | 1612191-86-2 |
| MW: | 392.6 D |
ab 44,00 €
