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Unesbulin
Artikelnummer: TGM-T12575-100mg
Description: Unesbulin (PTC596) is an orally active, selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1). Target: Apoptosis, BMI-1. Smiles: Cc1nc2ccc(F)cc2n1-c1nc(N)c(F)c(Nc2ccc(cc2)C(F)(F)F)n1. References: Nishida Y, et al. The novel BMI-1 inhibitor PTC596 downregulates...
| Schlagworte: | PTC596 |
| Anwendung: | Targets polycomb group RING finger protein 4 (PCGF4, BMI1) |
| CAS | 1610964-64-1 |
| MW: | 420.34 D |
ab 88,00 €
PTC-596
Artikelnummer: Cay33529-1
PTC-596 is an inhibitor of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), which is a member of the polycomb repressive complex 1 (PRC1) that has a role in gene silencing. It inhibits proliferation of MOLM-13 acute myeloid leukemia (AML) and Rec-1 mantle cell lymphoma (MCL) cancer cells...
| Schlagworte: | Unesbulin, 5-fluoro-2-(6-fluoro-2-methyl-1H-benzimidazol-1-yl)-N4-[4-(trifluoromethyl)phenyl]-4,6-pyrimidinediamine |
| Anwendung: | BMI1 inhibitor |
| CAS | 1610964-64-1 |
| MW: | 420.3 D |
ab 108,00 €
