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Hemin
Artikelnummer: TGM-T5515-1g
Description: Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme deficiency in patients, thereby inhibiting delta-aminolevulinic acid synthetase activity through biochemical feedback. Target: Autophagy,...
| Schlagworte: | Hemin chloride |
| Anwendung: | Targets 5-aminolevulinate synthase [EC:2.3.1.37] (E2.3.1.37, ALAS) |
| CAS | 16009-13-5 |
| MW: | 651.94 D |
ab 42,00 €
Hemin chloride
Artikelnummer: Cay16487-1
Hemin chloride is an oxidized form of heme that inhibits eukaryotic translation initiation factor 2alpha kinase 1 (eIF2alphaK1), a repressor of eIF-2alpha. This alters the initiation of mRNA translation, evoking a wide array of cellular effects. Hemin chloride is used experimentally to induce the expression of heme...
| Schlagworte: | (SP-5-13)-chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,8-dipropanoato(4-)-kappaN21, kappaN22, kappaN23,... |
| Anwendung: | EIF2AK1 inhibitor |
| CAS | 16009-13-5 |
| MW: | 652 D |
ab 67,00 €
