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MC-Val-Cit-PABC-PNP
Artikelnummer: TGM-T3503-50mg
Description: MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage...
| Schlagworte: | Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate |
| CAS | 159857-81-5 |
| MW: | 737.76 D |
30,00 €
Mc-Val-Cit-PABC-PNP
Artikelnummer: Cay23881-1
Mc-Val-Cit-PABC-PNP is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to anticancer compounds, such as doxorubicin (Cay-15007) or...
| Schlagworte: | Maleimidocaproyl-L-Valine-L-Citrulline-p-Aminobenzyl Alcohol p-Nitrophenyl Carbonate,... |
| Anwendung: | Peptide linker, antibody-drug conjugate synthesis |
| CAS | 159857-81-5 |
| MW: | 737.8 D |
ab 44,00 €
