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MONNA
Artikelnummer: TGM-T8960-100mg
Description: MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions. Target: Chloride channel. Smiles: COc1cc(Nc2ccc(cc2C(O)=O)[N+]([O-])=O)cc2ccccc12. References: TMEM16A is implicated in the regulation of...
| Anwendung: | TMEM16A blocker |
| CAS | 1572936-83-4 |
| MW: | 338.31 D |
ab 35,00 €
MONNA
Artikelnummer: Cay21917-1
MONNA is a selective inhibitor of anoctamin-1 (ANO1, IC50 = 0.08 µM in Xenopus oocytes), a calcium-activated chloride channel (CaCC). It is selective for ANO1 over the chloride channels bestrophin-1, chloride channel protein 2, and cystic fibrosis transmembrane conductance regulator up to 10 µM. MONNA (10 µM)...
| Schlagworte: | 2-[(4-methoxy-2-naphthalenyl)amino]-5-nitro-benzoic acid |
| Anwendung: | TMEM16A blocker |
| CAS | 1572936-83-4 |
| MW: | 338.3 D |
ab 44,00 €
