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G244-LM
Artikelnummer: TGM-T8964-10mg
Description: G244-LM, a potent and specific inhibitor of tankyrase 1/2, effectively inhibits Wnt signaling. Target: Others, PARP. Smiles: CS(=O)(=O)c1ccccc1N1CCN(CC1)c1nc2CCSCc2c(=O)[nH]1. References: Lau T , Chan E , Callow M , et al. A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation-Driven...
| Anwendung: | Tankyrase 1/2 inhibitor |
| CAS | 1563007-08-8 |
| MW: | 406.52 D |
ab 45,00 €
G244-LM
Artikelnummer: Cay21876-1
G244-LM is an inhibitor of Wnt signaling. It inhibits Wnt3a-induced signaling in HEK293 human and 10T1/2 mouse cells in a reporter assay. It also inhibits Wnt signaling and colony formation in COLO-320DM and SW403, but not HCT-15 or DLD-1, colorectal cancer cells when used at a concentration of 0.2 µM for seven to...
| Schlagworte: | 3,5,7,8-tetrahydro-2-[4-[2-(methylsulfonyl)phenyl]-1-piperazinyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Anwendung: | Tankyrase 1/2 inhibitor |
| CAS | 1563007-08-8 |
| MW: | 406.5 D |
ab 67,00 €
