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Avitinib
Artikelnummer: TGM-T3024-100mg
Description: Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potential antineoplastic activity. Upon oral administration, avitinib covalently binds to and inhibits the activity of mutant forms of EGFR,...
| Schlagworte: | AC0010 |
| Anwendung: | Antineoplastic |
| CAS | 1557267-42-1 |
| MW: | 487.53 D |
ab 42,00 €
Avitinib
Artikelnummer: Cay21387-1
Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR). It is selective for EGFR-active and T790M mutations, exhibiting a 298-fold increase in potency compared with wild-type EGFR. In a xenograft model, oral administration of 500 mg/kg avitinib was shown to...
| Schlagworte: | AC0010, N-[3-[[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]-2-propenamide |
| Anwendung: | EGFR mutant-selective inhibitor |
| CAS | 1557267-42-1 |
| MW: | 487.5 D |
ab 52,00 €
