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BRD3308
Artikelnummer: TGM-T8233-100mg
Description: BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK. Target: Apoptosis, HDAC, HIV Protease. Smiles: CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N. References: Lundh M, et al. Histone deacetylase 3 inhibition improves glycaemia and insulin...
| Anwendung: | HDAC3 inhibitor |
| CAS | 1550053-02-5 |
| MW: | 287.29 D |
ab 38,00 €
BRD3308
Artikelnummer: Cay34875-5
BRD3308 is an inhibitor of histone deacetylase 3 (HDAC3, Ki = 29 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (Kis = 6,300 and 5,100 nM, respectively). BRD3308 (10 µM) reduces cytokine-induced increases in apoptosis in rat INS-1E beta cells. In vivo, BRD3308 (5 mg/kg) reduces plasma glucose levels in rats and...
| Schlagworte: | 4-(acetylamino)-N-(2-amino-4-fluorophenyl)-benzamide |
| Anwendung: | HDAC3 inhibitor |
| CAS | 1550053-02-5 |
| MW: | 287.3 D |
ab 98,00 €
