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Abiraterone
Abiraterone

Artikelnummer: TGM-T6216-100mg

Description: Abiraterone (CB-7598) (CB-7598) is an effective steroidal cytochrome P450 17alpha-hydroxylase-17, 20-lyase (CYP17) inhibitor (IC50: 4 nM). Target: P450. Smiles: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC=C2C=5C=CC=NC5)[H]. References: Attard G, et al. J Clin Oncol. 2008,...
Schlagworte: CB-7598
Anwendung: CYP17A1 inhibitor
CAS 154229-19-3
MW: 349.51 D
ab 34,00 €
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Abiraterone
Abiraterone

Artikelnummer: Cay9002768-1

Abiraterone is an inhibitor of the cytochrome P450 (CYP) isoform CYP17A1 (IC50s = 0.0029 and 0.004 µM for the 17,20-lyase and 17alpha-hydroxylase activities, respectively) and active metabolite of abiraterone acetate (Cay-15148). It is formed from abiraterone acetate by arylacetamide deacetylase. Abiraterone is...
Schlagworte: CB-7598, (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol
Anwendung: CYP17A1 inhibitor
CAS 154229-19-3
MW: 349.5 D
ab 44,00 €
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Abiraterone
Abiraterone

Artikelnummer: LKT-A0534.5

A selective steroidal inhibitor of cytochrome P450 (17) alpha (17 alpha-hydroxylase/C17-20 lyase) is highly active in the treatment of castration-resistant prostate cancer.
CAS 154229-19-3
MW: 349.51 D
ab 125,00 €
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