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Bexarotene
Artikelnummer: TGM-T6410-100mg
Description: Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL). Target: Retinoid Receptor, Autophagy. Smiles: CC1(C)C=2C(C(C)(C)CC1)=CC(C)=C(C(=C)C3=CC=C(C(O)=O)C=C3)C2. References: Zhang C, et al. Clin Cancer Res, 2002, 8(5), 1234-1240.
| Schlagworte: | Targretin, Ro 26-4455, LGD1069 |
| Anwendung: | Antineoplastic |
| CAS | 153559-49-0 |
| MW: | 348.48 D |
ab 31,00 €
Bexarotene
Artikelnummer: Cay11571-50
Bexarotene is an agonist of retinoid X receptors (RXRs, EC50s = 28, 25, and 20 nM for RXRalpha, RXRbeta, and RXRgamma, respectively, in reporter assays). It is selective for RXRs over retinoic acid receptors (RARs, EC50s = >10 µM for RARalpha, RARbeta, and RARgamma). Bexarotene (10 µM) induces apoptosis in MJ, HuT...
| Schlagworte: | LG 100069, LGD 1069, Ro 26-4455, SR 11247, 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-benzoic... |
| Anwendung: | Retinoid X receptor ligand |
| CAS | 153559-49-0 |
| MW: | 348.5 D |
ab 34,00 €
Bexarotene
Artikelnummer: LKT-B1992.25
Bexarotene is an oral antineoplastic agent used for cutaneous T cell lymphoma. Researchers have discovered that bexarotene reduced amyloid plaque and that could be used to treat Alzheimer's symptoms.
| Schlagworte: | Targretin, Targretyn, LGD-1069 |
| CAS | 153559-49-0 |
| MW: | 348.48 D |
ab 94,00 €
Bexarotene, Free Acid (Targretin, Targretyn, Targrexin,...
Artikelnummer: B1085-32C.100
Bexarotene (LGD-1069) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas...
| CAS | 153559-49-0 |
| MW: | 348.48 |
275,00 €
