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SB203580
Artikelnummer: AG-CR1-0030-M001
Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferative, PDK1 inhibitor, Anti-inflammatory, Review.
| Schlagworte: | 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole |
| Anwendung: | p38 MAP kinase inhibitor |
| CAS | 152121-47-6 |
| MW: | 377,4 D |
ab 39,00 €
SB 203580
Artikelnummer: Cay13067-5
Mitogen-activated protein kinases (MAPK) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
| Schlagworte: | PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine |
| Anwendung: | p38 MAPK inhibitor |
| CAS | 152121-47-6 |
| MW: | 377.4 D |
ab 92,00 €
SB-203580
Artikelnummer: LKT-S0500.5
SB-203580 is an inhibitor of p38 MAPK that exhibits immunostimulatory, anticancer, and anti-fibrotic activities. In peripheral blood mononuclear cells, SB-203580 increases secretion of IFN- . In lung epithelial cells, SB-203580 inhibits TGB- 1-induced epithelial-to-mesenchymal transition (EMT). Additionally,...
| Schlagworte: | SB203580 |
| Anwendung: | p38 MAP kinase inhibitor |
| CAS | 152121-47-6 |
| MW: | 377.43 D |
ab 108,00 €
SAPK2, p38 Inhibitor (SB 203580 Free Base,...
Artikelnummer: S0096-26A.25
Important, highly specific inhibitor of the kinase known variously as p38, p40, CSBP, or RK. This kinase is a homolog of MAP kinase. Gallagher, T.F., et al. "2,4,5-Triarylimidazole inhibitors of Il-1 biosynthesis." Bioorg. Med. Chem. Lett. 5: 1171-1176 (1995). Cuenda, A., et al. "SB203580 is a specific inhibitor of...
| CAS | 152121-47-6 |
| MW: | 377.43 |
234,00 €
