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iFSP1
iFSP1

Artikelnummer: Cay29483-10

iFSP1 is an inhibitor of apoptosis inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1). It decreases cell viability in wild-type, but not glutathione peroxidase 4 (GPX4) knock-out, Pfa1 and HT1080 cells overexpressing AIFM2/FSP1, an effect that can be blocked by the ferroptosis...
Schlagworte: 1-amino-3-(4-methylphenyl)-pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
Anwendung: AIFM2 inhibitor
CAS 150651-39-1
MW: 323.4 D
ab 44,00 €
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iFSP1
iFSP1

Artikelnummer: TGM-T11631-100mg

Description: iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R)-RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1....
CAS 150651-39-1
MW: 323.35 D
ab 30,00 €
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