Zu "149647-78-9" wurden 4 Artikel gefunden!
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SAHA
Artikelnummer: Cay10009929-100
SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.Formal Name:...
| Schlagworte: | Suberoylanilide Hydroxamic Acid, Vorinostat, N1-hydroxy-N8-phenyl-octanediamide |
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264.3 D |
ab 34,00 €
Vorinostat
Artikelnummer: TGM-T1583-1g
Description: Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and induces apoptosis. Target: Virus Protease, Apoptosis, Autophagy, HDAC, Mitophagy....
| Schlagworte: | SAHA, MK0683, suberoylanilide hydroxamic acid |
| Anwendung: | Antineoplastic, Histone deacetylase inhibitor |
| CAS | 149647-78-9 |
| MW: | 264.32 D |
ab 44,00 €
Vorinostat
Artikelnummer: LKT-V5734.100
Vorinostat is a histone deacetylase inhibitor and has a broad spectrum of epigenetic activities. It is used in the treatment of cutaneous T cell lymphoma. It has also been shown to have both in vitro and in vivo effects against latently HIV infected T cells.
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264,32 D |
ab 129,00 €
Vorinostat
Artikelnummer: SYN-3006-M005
Solid. Soluble in DMSO or ethanol. Almost insoluble in water. Vorinostat (SAHA, MK0683, Zolinza) inhibits the enzymatic activity of histone deacetylases HDAC1, HDAC2 and HDAC3 (Class I) and HDAC6 (Class II) at nanomolar concentrations (IC50< 86 nM). These enzymes catalyze the removal of acetyl groups from the lysine...
| Schlagworte: | SAHA, MK0683, Zolinza |
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264,3 D |
ab 62,00 €
