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UNC2250
Artikelnummer: TGM-T1968-100mg
Description: UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM). Target: TAM Receptor. Smiles: CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(CN2CCOCC2)cn1. References: Zhang W, et al. J Med Chem. 2013, 56(23), 9683-9692.
| Anwendung: | Mer Kinase inhibitor |
| CAS | 1493694-70-4 |
| MW: | 440.58 D |
ab 40,00 €
UNC2250
Artikelnummer: Cay17703-1
Tyro3, Axl, and Mer are members of the TAM family of receptor tyrosine kinases that have signaling roles in normal and malignant cells. UNC2250 is an inhibitor of Mer kinase activity, blocking the steady-state phosphorylation of endogenous Mer in 697 B-ALL cells with an IC50 value of 9.8 nM. It is selective for Mer...
| Schlagworte: | trans-4-[[2-(butylamino)-5-[5-(4-morpholinylmethyl)-2-pyridinyl]-4-pyrimidinyl]amino]-cyclohexanol |
| Anwendung: | Mer Kinase inhibitor |
| CAS | 1493694-70-4 |
| MW: | 440.6 D |
ab 44,00 €
