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7ACC2
Artikelnummer: TGM-T1768-100mg
Description: 7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx, new antitumor treatment targeting lactate transport in Y cells. Target: Mitochondrial Metabolism, Monocarboxylate transporter. Smiles: CN(Cc1ccccc1)c1ccc2cc(C(O)=O)c(=O)oc2c1. References: Draoui N, et al. Bioorg Med Chem....
| Anwendung: | SLC16A1 / MCT1 inhibitor |
| CAS | 1472624-85-3 |
| MW: | 309.32 D |
ab 32,00 €
7ACC2
Artikelnummer: Cay23445-5
7ACC2 is a carboxycoumarin inhibitor of monocarboxylate transporter 1 (MCT1) with an IC50 value of 10 nM for lactate uptake, an MCT1-dependent process, in SiHa human cervix carcinoma cells. It inhibits proliferation of SiHa cells in the presence of lactate in a dose-dependent manner but lacks cytotoxicity in the...
| Schlagworte: | 7-[methyl(phenylmethyl)amino]-2-oxo-2H-1-benzopyran-3-carboxylic acid |
| Anwendung: | SLC16A1 / MCT1 inhibitor |
| CAS | 1472624-85-3 |
| MW: | 309.3 D |
ab 44,00 €
