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ETC-206
Artikelnummer: TGM-T15250-100mg
Description: ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM). Target: MNK. Smiles: O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2ncc(-c3ccc(cc3)C#N)n2c1. References: Yang H, et al. Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast...
| Anwendung: | MKNK1 / MKNK2 inhibitor |
| CAS | 1464151-33-4 |
| MW: | 408.45 D |
ab 31,00 €
ETC-206
Artikelnummer: Cay36501-10
ETC-206 is an inhibitor of MAPK-interacting serine/threonine kinase 1 (MKNK1) and MKNK2 (IC50s = 0.064 and 0.086 µM, respectively). It is selective for MKNK1 and MKNK2 over a panel of 104 kinases at 1 µM. ETC-206 inhibits phosphorylation of eukaryotic translation initiation factor 4E (eIF4E) in HeLa cells (IC50 =...
| Schlagworte: | 4-[6-[4-(4-morpholinylcarbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]-benzonitrile |
| Anwendung: | MKNK1 / MKNK2 inhibitor |
| CAS | 1464151-33-4 |
| MW: | 408.5 D |
ab 132,00 €
