Zu "146062-44-4" wurden 2 Artikel gefunden!
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Leriglitazone
Artikelnummer: TGM-T15736-1mg
Description: Leriglitazone, a metabolite of pioglitazone, binds to the PPARgamma C-terminal ligand-binding domain (Ki: 1.2 µM) and induces transcriptional efficacy of the PPARgamma (EC50: 680 nM). Leriglitazone PioOH is a PPARgamma agonist, stabilizes the PPARgamma activation function-2 (AF-2) co-activator binding...
| Schlagworte: | Hydroxypioglitazone |
| Anwendung: | Targets peroxisome proliferator-activated receptor gamma (NR1C3, PPARG) |
| CAS | 146062-44-4 |
| MW: | 372.44 D |
ab 687,00 €
Hydroxy Pioglitazone
Artikelnummer: Cay28043-1
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor gamma (PPARgamma) agonist pioglitazone (Cay-71745, Cay-22263, Cay-10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to...
| Schlagworte: | 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | Major metabolite |
| CAS | 146062-44-4 |
| MW: | 372.4 D |
ab 376,00 €
