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SH5-07
Artikelnummer: TGM-TQ0052-100mg
Description: SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 µM). Target: STAT. Smiles: CN(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(cc1)C(=O)NO)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F. References: Yue P,et al. Hydroxamic Acid and Benzoic Acid-Based STAT3 Inhibitors Suppress Human Glioma and Breast Cancer Phenotypes In...
| Anwendung: | STAT3 inhibitor |
| CAS | 1456632-41-9 |
| MW: | 625.61 D |
ab 31,00 €
SH5-07
Artikelnummer: Cay36818-10
SH5-07 is a STAT3 inhibitor (Ki = 10.46 µM). It is selective for STAT3 over STAT1 (Ki = >100 µM). SH5-07 prevents constitutively active STAT3 DNA binding in NIH3T3 fibroblast nuclear extracts (IC50 = 3.9 µM). It is cytotoxic to AR230 and imatinib-resistant AR230 chronic myeloid leukemia (CML) cells (IC50s = 8.1 and...
| Schlagworte: | 4-[[(4-cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxy-benzamide |
| Anwendung: | STAT3 inhibitor |
| CAS | 1456632-41-9 |
| MW: | 625.6 D |
ab 347,00 €
