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VU0467154
Artikelnummer: TGM-T17244-100mg
Description: VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (M4 mAChR). Target: AChR. Smiles: NC=1C=2C(SC1C(NCC3=CC=C(S(C(F)(F)F)(=O)=O)C=C3)=O)=NN=C(C)C2C. References: Bubser M, et al. Selective activation of M4 muscarinic acetylcholine receptors reverses MK-801-induced...
| Anwendung: | Muscarinic acetylcholine receptor M4 positive allosteric modulator |
| CAS | 1451993-15-9 |
| MW: | 444.45 D |
ab 41,00 €
VU0467154
Artikelnummer: Cay25555-1
VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor that potentiates acetylcholine responses in CHO cells expressing M4 receptors (EC50s = 17.7, 630, and 1,000 nM for rat, human, and cynomolgus monkey receptors, respectively). It is selective for M4 over M1-3 and M5 receptors and...
| Schlagworte: | 5-amino-3,4-dimethyl-N-[[4-[(trifluoromethyl)sulfonyl]phenyl]methyl]-thieno[2,3-c]pyridazine-6-carboxamide |
| Anwendung: | Muscarinic acetylcholine receptor M4 positive allosteric modulator |
| CAS | 1451993-15-9 |
| MW: | 444.5 D |
ab 80,00 €
