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Ivosidenib
Artikelnummer: TGM-T3617-100mg
Description: Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. It specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of the oncometabolite 2-hydroxyglutarate (2 hG), which may induce cellular...
| Schlagworte: | AG-120 |
| Anwendung: | Targets isocitrate dehydrogenase [EC:1.1.1.42] (IDH1, IDH2, icd) |
| CAS | 1448347-49-6 |
| MW: | 582.96 D |
ab 42,00 €
AG-120
Artikelnummer: Cay19894-10
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) that specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of 2-hydroxyglutarate. AG-120 may induce cellular differentiation as well as inhibit proliferation in IDH1-expressing tumor cells.Formal Name:...
| Schlagworte: | Invosidenib,... |
| Anwendung: | IDH1 inhibitor |
| CAS | 1448347-49-6 |
| MW: | 583 D |
ab 44,00 €
