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Mivebresib
Artikelnummer: TGM-T3712-100mg
Description: Mivebresib (ABBV-075), also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby...
| Schlagworte: | ABBV-075 |
| Anwendung: | Targets bromodomain-containing protein 4 (BRD4) |
| CAS | 1445993-26-9 |
| MW: | 459.47 D |
ab 54,00 €
ABBV-075
Artikelnummer: Cay21033-10
ABBV-075 is a potent inhibitor of the bromodomain and extra terminal domain (BET) family of proteins that is selective for the bromodomain-containing proteins (BRD) BRD2, BRD4, and BRDT (Kis = 1-2.2 nM) over BRD3 (Ki = 12.2 nM) and against a panel of 18 BRD proteins. It inhibits BRD4 recruitment to androgen...
| Schlagworte: | Mivebresib, N-[4-(2,4-difluorophenoxy)-3-(6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]-ethanesulfonamide |
| Anwendung: | BET inhibitor |
| CAS | 1445993-26-9 |
| MW: | 459.5 D |
ab 44,00 €
