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GSK2837808A
Artikelnummer: TGM-T15435-100mg
Description: GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 values of 1.9 nM for LDHA and 14 nM for LDHB. Target: Dehydrogenase. Smiles: COc1ncc(-c2ccc3c(Nc4cc(Oc5cc(F)cc(F)c5)cc(c4)C(O)=O)c(cnc3c2)S(=O)(=O)NC2CC2)c(OC)n1. References: Billiard J, et al. Quinoline...
| Anwendung: | Potent, selective cell-permeable LDHA inhibitor |
| CAS | 1445879-21-9 |
| MW: | 649.62 D |
ab 42,00 €
GSK2837808A
Artikelnummer: Cay20626-1
GSK2837808A is a potent inhibitor of lactate dehydrogenase (LDH) A and B (IC50s = 2.6 and 0.43 nM, for human recombinant LDHA and LDHB, respectively). It inhibits lactate production in Snu398 hepatocellular carcinoma cells in which LDHB expression is undetectable (EC50 = 400 nM). GSK2837808A (10 µM) reduces glucose...
| Schlagworte: | 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)-benzoic acid |
| Anwendung: | LDHA inhibitor |
| CAS | 1445879-21-9 |
| MW: | 649.6 D |
ab 61,00 €
GSK2837808A
Artikelnummer: AG-CR1-3685-M005
Potent and selective cell permeable inhibitor of lactate dehydrogenase A (LDHA) (IC50 values are 2.6 and 43 nM for LDHA and LDHB, respectively). Decreases glycolysis. Useful agent for immunometabolism research. Exhibits antitumoral activity. Inhibits lactate production in selected cancer cell lines. Reduces glucose...
| Schlagworte: | 3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid |
| Anwendung: | Potent, selective cell-permeable LDHA inhibitor |
| CAS | 1445879-21-9 |
| MW: | 649.6 D |
ab 50,00 €
