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CEP-40783
Artikelnummer: TGM-T4426-100mg
Description: CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM). Target: c-Met/HGFR, TAM Receptor. Smiles: COc1cc2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c2cc1OC. References: Miknyoczki S, Cheng M,...
| Schlagworte: | RXDX-106, CEP 40783 |
| Anwendung: | AXL / c-Met inhibitor |
| CAS | 1437321-24-8 |
| MW: | 588.56 D |
ab 34,00 €
CEP-40783
Artikelnummer: Cay25749-1
CEP-40783 is an inhibitor of the receptor tyrosine kinases Axl and c-MET (IC50s = 7 and 12 nM, respectively). It inhibits Axl in 293GT cells expressing Axl and c-MET in NCI H1299 non-small cell lung cancer (NSCLC) cells with IC50 values of 0.26 and 6 nM, respectively. It also inhibits the receptor tyrosine kinases...
| Schlagworte: | RXDX-106,... |
| Anwendung: | AXL / c-Met inhibitor |
| CAS | 1437321-24-8 |
| MW: | 588.6 D |
ab 52,00 €
