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Pregnenolone Carbonitrile
Artikelnummer: TGM-T21818-1mL
Description: Pregnenolone Carbonitrile (5-Pregnen-3beta-ol-20-one-16alpha-carbonitrile) is an activator of rodent-PXR and induces the expression of CYP3A. Target: P450. Smiles: [H][C@@]12C[C@@H](C#N)[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C. References: Carylyn J Marek, et al....
| Schlagworte: | 5-Pregnen-3beta-ol-20-one-16alpha-carbonitrile, Pregnenolone 16alpha-carbonitrile |
| CAS | 1434-54-4 |
| MW: | 341.49 D |
ab 45,00 €
Pregnenolone Carbonitrile
Artikelnummer: Cay16343-25
Pregnenolone carbonitrile (PCN) is a catatoxic steroid that acts as an agonist of the rodent pregnane X receptor (PXR) at µM concentrations. It has been shown to mediate induction of hepatic cytochrome P450 3A, organic anion transporting peptide-2, and cholesterol 7alpha-hydroxylase, regulating both xenobiotic and...
| Schlagworte: | PCN, Pregnenolone 16alpha-carbonitrile, SC-4674, 3beta-hydroxy-20-oxo-pregn-5-ene-16alpha-carbonitrile |
| Anwendung: | Rodent pregnane X receptor (PXR) agonist |
| CAS | 1434-54-4 |
| MW: | 341.5 D |
ab 55,00 €
