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LDN-212854
Artikelnummer: TGM-T1900-100mg
Description: LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-beta type I receptors, possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors. Target: ALK, TGF-beta/Smad. Smiles:...
| Schlagworte: | BMP Inhibitor III, LDN212854 |
| Anwendung: | ALK2 inhibitor |
| CAS | 1432597-26-6 |
| MW: | 406.48 D |
ab 42,00 €
LDN-212854
Artikelnummer: Cay17698-1
Activation of bone morphogenetic protein (BMP) type I receptors, also known as activin receptor-like kinases (ALK1-7), leads to the assembly of SMAD complexes, which translocate to the nucleus to induce transcriptional activation important for normal development and tissue repair. LDN-212854 inhibits ALK2 (IC50 =...
| Schlagworte: | 5-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
| Anwendung: | ALK2 inhibitor |
| CAS | 1432597-26-6 |
| MW: | 406.5 D |
ab 49,00 €
