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ML334
Artikelnummer: TGM-T12078-1mg
Description: ML334 (LH601A) is a transmembrane and potent NRF2 activator that inhibits Keap1-NRF2 protein interactions to ameliorate myocardial infarction-induced cardiac fibrosis by inhibiting cardiac fibroblast activation and proliferation. Target: Nrf2. Smiles:...
| Schlagworte: | LH601A |
| Anwendung: | Nrf2-Keap1 protein-protein interaction inhibitor |
| CAS | 1432500-66-7 |
| MW: | 446.49 D |
51,00 €
ML-334
Artikelnummer: Cay31439-1
ML-334 is an inhibitor of the protein-protein interaction between the transcription factor Nrf2 and its inhibitor Keap1. It binds to the Keap1 Kelch domain (IC50 = 1 µM) to induce dissociation and nuclear translocation of Nrf2 and activation of the antioxidant response element (ARE) in a cell-based assay (EC50 = 12...
| Schlagworte: | LH601, (1S,2R)-2-[[(1S... |
| Anwendung: | Nrf2-Keap1 protein-protein interaction inhibitor |
| CAS | 1432500-66-7 |
| MW: | 446.5 D |
ab 52,00 €
