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VLX1570
Artikelnummer: TGM-T4067-100mg
Description: VLX1570 is a competitive inhibitor of proteasome DUB activity, with an IC50 ranging from 4.2 µM to 8.6 µM, and exhibits potent inhibition of USP14. Target: DUB. Smiles: [O-][N+](=O)c1cc(\C=C2\CCN(C\C(=C\c3ccc(F)c(c3)[N+]([O-])=O)C2=O)C(=O)C=C)ccc1F. References: Wang X et al. Synthesis and evaluation of...
| Anwendung: | 19S proteasomal deubiquitinase inhibitor |
| CAS | 1431280-51-1 |
| MW: | 469.39 D |
ab 95,00 €
VLX1570
Artikelnummer: Cay29721-1
VLX1570 is an inhibitor of 19S proteasomal deubiquitinases with IC50 values of 6.4 and 13 µM for deubiquitinase activity in vitro using Ub-rhodamine and Ub-AMC, respectively, as substrates. It is selective for proteasomal deubiquitinases over a panel of deubiquitinases at 20 µM, but inhibits USP5 by greater than...
| Schlagworte: | 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-4H-azepin-4-one |
| Anwendung: | 19S proteasomal deubiquitinase inhibitor |
| CAS | 1431280-51-1 |
| MW: | 469.4 D |
ab 48,00 €
