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PF 05089771 tosylate
Artikelnummer: TGM-T7502-10mg
Description: PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8 channels (IC50: 0.11-25 µM), L-type calcium, and KvLQT and hERG potassium channels...
| Anwendung: | Nav1.7 blocker |
| CAS | 1430806-04-4 |
| MW: | 672.56 D |
ab 56,00 €
PF-05089771 (tosylate)
Artikelnummer: Cay24449-10
PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50s = 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8 channels (IC50s = 0.11-25 µM), L-type calcium, and KvLQT and hERG potassium channels (IC50s =...
| Schlagworte: | 4-[2-(3-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolyl-4-benzenesulfonamide,... |
| Anwendung: | Nav1.7 blocker |
| CAS | 1430806-04-4 |
| MW: | 672.6 D |
ab 131,00 €
