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ODM-203
Artikelnummer: TGM-T7611-100mg
Description: ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity. Target: VEGFR, FGFR. Smiles: Cn1cc(cn1)-c1ccc2n(cnc2c1)-c1cc(NS(=O)(=O)C2CC2)cc(c1)-c1ccc(F)cc1F. References: Tim H Holmström , Anu-Maarit Moilanen , Tarja Ikonen,et al.ODM-203, a...
| Anwendung: | VEGFR / FGFR dual inhibitor |
| CAS | 1430723-35-5 |
| MW: | 505.54 D |
ab 36,00 €
ODM-203
Artikelnummer: Cay31451-10
ODM-203 is a dual inhibitor of VEGFR and FGFR (IC50s = 5-26 and 6-35 nM for VEGFR1-3 and FGFR1-4, respectively). It is selective for VEGFR1-3 and FGFR1-4 over a panel of 308 kinases at 1 µM, but does inhibit the receptor tyrosine kinases PDGFRalpha, PDGFRbeta, and DDR1 (IC50s = 35, 169, and 6 nM, respectively), as...
| Schlagworte: | N-[2',4'-difluoro-5-[5-(1-methyl-1H-pyrazol-4-yl)-1H-benzimidazol-1-yl][1,1'-biphenyl]-3-yl]-cyclopropanesulfonamide |
| Anwendung: | VEGFR / FGFR dual inhibitor |
| CAS | 1430723-35-5 |
| MW: | 505.5 D |
ab 163,00 €
