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CZ415
Artikelnummer: TGM-T3514-100mg
Description: CZ415 is a potent and highly selective mTOR inhibitor. This compound has a molecular weight of 432.51 g/mol and demonstrates an inhibition constant (IC50) of 5.8 nM against mTOR. Additionally, CZ415 has shown to be efficacious in preclinical models of cancer, indicating its potential therapeutic...
| Anwendung: | mTOR inhibitor |
| CAS | 1429639-50-8 |
| MW: | 459.56 D |
ab 58,00 €
CZ415
Artikelnummer: Cay27668-1
CZ415 is an inhibitor of mammalian target of rapamycin (mTOR, Kd = 6.3 nM). It is 1,000-fold selective for mTOR over a panel of 285 kinases. CZ415 inhibits phosphorylation of S6 ribosomal protein (S6RP) and Akt in HEK293T cells (IC50s = 14.5 and 14.8 nM, respectively). It inhibits IFN-gamma secretion in IL-2,...
| Schlagworte: | N-[4-[5,7-dihydro-7,7-dimethyl-4-[(3S)-3-methyl-4-morpholinyl]-6,6-dioxidothieno[3,4-d]pyrimidin-2-yl]phenyl]-N'-ethyl-urea |
| Anwendung: | mTOR inhibitor |
| CAS | 1429639-50-8 |
| MW: | 459.6 D |
ab 60,00 €
