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IWP L6
Artikelnummer: TGM-T2683-10mg
Description: IWP L6 (Porcn Inhibitor III) is a highly potent Porcn inhibitor with an EC50 of 0.5 nM. Target: Porcupine. Smiles: O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccccc1. References: Wang X, et al. J Med Chem. 2013, 56(6), 2700-2704.
| Schlagworte: | Porcn Inhibitor III, IWP-L6, Porcn Inhibitor III |
| CAS | 1427782-89-5 |
| MW: | 472.58 D |
ab 42,00 €
IWP-L6
Artikelnummer: Cay15243-5
Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. IWP-L6 is a potent inhibitor of PORCN (EC50 = 0.5 nM). It suppresses the...
| Schlagworte: | PORCN Inhibitor III, Wnt Pathway Inhibitor XIX,... |
| Anwendung: | Potent PORCN inhibitor |
| CAS | 1427782-89-5 |
| MW: | 472.6 D |
ab 112,00 €
