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Parsaclisib
Artikelnummer: Cay29784-1
Parsaclisib is an inhibitor of PI3Kdelta (IC50 = 1 nM). It is selective for PI3Kdelta over PI3Kalpha, PI3Kbeta, and PI3Kgamma (IC50s = >10,000 nM for all), as well as a panel of 192 additional kinases and a panel of 70 ion channels and transporters at 1 µM. Parsaclisib inhibits the proliferation of primary human B...
| Schlagworte: | INCB 050465,... |
| Anwendung: | PI3Kdelta inhibitor |
| CAS | 1426698-88-5 |
| MW: | 432.9 D |
ab 103,00 €
Parsaclisib
Artikelnummer: TGM-T12367-100mg
Description: Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kdelta(IC50 of 1 nM at 1 mM ATP). Target: PI3K. Smiles: CCOc1c(cc(Cl)c(F)c1[C@@H]1CNC(=O)C1)[C@H](C)n1nc(C)c2c(N)ncnc12. References: Niu Shin, et al. Abstract 2671: INCB050465, a novel PI3Kdelta inhibitor, synergizes with PIM protein...
| Schlagworte: | INCB050465 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1426698-88-5 |
| MW: | 432.88 D |
ab 147,00 €
