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L-701324
L-701324

Artikelnummer: TGM-T1909-100mg

Description: L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant. Target: NMDAR, iGluR. Smiles: Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12. References: Wlaz P, Poleszak E. Pharmacol Rep. 2011,63(5):1231-4.
Schlagworte: L701324
Anwendung: NMDA receptor antagonist
CAS 142326-59-8
MW: 363.79 D
ab 34,00 €
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L-701,324
L-701,324

Artikelnummer: Cay30687-10

L-701,324 is an NMDA receptor antagonist. It inhibits NMDA-induced currents in rat cortical neurons (Ki = 5.4 nM). L-701,324 inhibits seizures induced by N-methyl-DL-aspartate, pentylenetetrazole (PTZ, Cay-18682), or electroshock, as well as audiogenic seizures in mice (ED50s = 3.5, 2.8, 1.4, and 0.96 mg/kg,...
Schlagworte: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone
Anwendung: NMDA receptor antagonist
CAS 142326-59-8
MW: 363.8 D
ab 128,00 €
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