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HJC0152 hydrochloride
Artikelnummer: TGM-T4234-10mg
Description: HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor. Target: Apoptosis, STAT. Smiles: Cl.NCCOc1ccc(Cl)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O. References: Chen H, et al. Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally...
| Schlagworte: | HJC0152 |
| Anwendung: | STAT3 inhibitor |
| CAS | 1420290-99-8 |
| MW: | 406.64 D |
ab 33,00 €
HJC0152 (hydrochloride)
Artikelnummer: Cay22351-1
HJC0152 is an orally bioavailable inhibitor of STAT3 (32 and 62% inhibition at 10 and 20 µM, respectively, in MDA-MB-231 cells in a luciferase reporter assay). It reduces total STAT3 and phosphorylated STAT3 levels in MDA-MB-231 cells and inhibits nuclear translocation of phosphorylated STAT3. HJC0152 inhibits...
| Schlagworte: | 2-(2-aminoethoxy)-5-chloro-N-(2-chloro-4-nitrophenyl)-benzamide, monohydrochloride |
| Anwendung: | STAT3 inhibitor |
| CAS | 1420290-99-8 |
| MW: | 406.6 D |
ab 84,00 €
