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HDAC8-IN-1
Artikelnummer: TGM-T7082-100mg
Description: MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for...
| Anwendung: | HDAC8 inhibitor |
| CAS | 1417997-93-3 |
| MW: | 345.39 D |
ab 65,00 €
HDAC8-IN-1
Artikelnummer: Cay28832-10
HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8, IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = >3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 µM, respectively).Formal Name:...
| Schlagworte: | MDK-7933, (2E)-N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide |
| Anwendung: | HDAC8 inhibitor |
| CAS | 1417997-93-3 |
| MW: | 345.4 D |
ab 60,00 €
