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RI-2
Artikelnummer: TGM-T2628-100mg
Description: RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 µM in the standard DNA binding assay, specifically inhibits HR(Homologous recombination) repair in human cells. Target: DNA/RNA Synthesis. Smiles: COc1ccc(cc1)C1=C(N2CCOCC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1. References: Budke B, et al. J Med Chem....
| Anwendung: | RAD51 inhibitor |
| CAS | 1417162-36-7 |
| MW: | 433.28 D |
ab 67,00 €
RI-2
Artikelnummer: Cay18397-1
RI-2 is a reversible inhibitor of RAD51 (IC50 = 44.2 µM), a protein that is central to the homologous recombination process initiated upon DNA double-strand breaks and is often overexpressed in a wide range of human cancer cell types. At 150 µM, it has been shown to inhibit DNA repair and to sensitize cancer cells...
| Schlagworte: | 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione |
| Anwendung: | RAD51 inhibitor |
| CAS | 1417162-36-7 |
| MW: | 433.3 D |
ab 67,00 €
