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Levosimendan
Levosimendan

Artikelnummer: Cay16128-50

Levosimendan is a calcium sensitizer that can cause increased cardiac contractility by binding troponin C (EC50 = 9 nM), promotes vasodilation by activating ATP-sensitive potassium channels on vascular smooth muscle cells (EC50 = 0.28 µM), and performs a cardioprotective function by prompting the opening of...
Schlagworte: (R)-Simendan, OR 1259, Simdax(R),...
Anwendung: PDE3 inhibitor
CAS 141505-33-1
MW: 280.3 D
ab 77,00 €
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Levosimendan
Levosimendan

Artikelnummer: LKT-L1884.250

A Ca(2) sensitizer that increases contractile force of the myocardium by enhancing the sensitivity ofmyofilaments to calcium without increasing intracellular calcium concentration. It has been shown to reduce circulating proinflammatory cytokine interleukin-6 and soluble apoptosis mediators.
Anwendung: Ca sensitizer
CAS 141505-33-1
MW: 280,28 D
ab 189,00 €
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Levosimendan
Levosimendan

Artikelnummer: LKT-L1884.25

A Ca(2) sensitizer that increases contractile force of the myocardium by enhancing the sensitivity ofmyofilaments to calcium without increasing intracellular calcium concentration. It has been shown to reduce circulating proinflammatory cytokine interleukin-6 and soluble apoptosis mediators.
Schlagworte: Simdax, Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6- oxo-3-pyridazinyl)phenyl)hydrazone
Anwendung: Ca sensitizer
CAS 141505-33-1
MW: 280.28 D
89,00 €
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