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NK-252
Artikelnummer: TGM-T16331-100mg
Description: NK-252 is a potential activator of Nrf2. It has great Nrf2-activating potential. Target: Nrf2, Others. Smiles: O=C(NCc1ccccn1)Nc1nnc(o1)-c1ccco1. References: Shimozono R et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol...
| Anwendung: | Nrf2 activator |
| CAS | 1414963-82-8 |
| MW: | 285.26 D |
ab 35,00 €
NK 252
Artikelnummer: Cay19131-5
NK 252 is a Nrf2 activator that interacts directly with the domain containing the Nrf2-binding site of Keap1. At 1.36 µM, it is reported to activate the NQO1-antioxidant response element in a luciferase reporter gene assay two-fold above background. NK 252 has been shown to downregulate the expression of fibrogenic...
| Schlagworte: | N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)-urea |
| Anwendung: | Nrf2 activator |
| CAS | 1414963-82-8 |
| MW: | 285.3 D |
ab 44,00 €
