Zu "1402345-92-9" wurden 3 Artikel gefunden!
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GSK-F1
Artikelnummer: Cay41366-1
GSK-F1 is a PI4KIIIalpha inhibitor (IC50 = 5.01 nM). It is selective for PI4KIIIalpha over PI4Kbeta, PI3Kalpha, PI3Kbeta, PI3Kdelta, and PI4Kgamma (IC50s = 1,000, 2,512, 7,943, 2,512, and 2,512 nM, respectively). GSK-F1 inhibits the replication of hepatitis C virus (HCV) genotypes 1a, 1b, and 2a in a cell-based...
| Schlagworte: | 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulf... |
| Anwendung: | PI4KA inhibitor |
| CAS | 1402345-92-9 |
| MW: | 603.5 D |
ab 136,00 €
GSK-F1
Artikelnummer: TGM-T19840-100mg
Description: GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor. Target: PI4K. Smiles: COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccc2nc(N)n(-c3ccccc3C(F)(F)F)c(=O)c2c1. References: Anna Lindsey Banka, et al. Quinazolinone derivatives as antiviral agents.WO2012087938A1
| Schlagworte: | PI4KA inhibitor-F1 |
| Anwendung: | Potent PI4KA inhibitor |
| CAS | 1402345-92-9 |
| MW: | 603.52 D |
ab 112,00 €
GSK-F1
Artikelnummer: SYN-1220-M001
Solid. Soluble in DMSO. GSK-F1 is a potent PI4KA inhibitor. It has better pharmacokinetic properties in vivo than to GSK-A1 (SYN-1219). GSK-F1 does not cross the blood-brain barrier. Phosphatidylinositol 4-kinase type III? (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for...
| Schlagworte: | 5-(2-Amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulf... |
| Anwendung: | Potent PI4KA inhibitor |
| CAS | 1402345-92-9 |
| MW: | 603,5 D |
ab 185,00 €
