Zu "1401463-54-4" wurden 2 Artikel gefunden!
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BAN ORL 24
Artikelnummer: TGM-T10457-1mL
Description: BAN ORL 24 is a potent and selective NOP receptor antagonist (IC50s: 0.27, 2500, 6700 and > 10000 nM for NOP, kappa-, µ- and delta-receptors). Target: Others. Smiles: Cl.Cl.O=C(NCCCN1CCC2(CC1)OCc1ccccc21)[C@H]1CCCN1Cc1ccccc1. References: Fischetti et al (2009) Pharmacological characterization of the...
| CAS | 1401463-54-4 |
| MW: | 506.51 D |
ab 46,00 €
BAN ORL 24 (hydrochloride)
Artikelnummer: Cay29485-1
BAN ORL 24 is an antagonist of the nociceptin (NOP) receptor (Ki = 0.24 nM in a radioligand binding assay using CHO cell membranes expressing the human receptor). It is selective for NOP receptors over µ-, delta-, and kappa-opioid receptors (Kis = 0.19, 0.34, and >1 µM, respectively). BAN ORL 24 reduces NOP-induced...
| Schlagworte: | 1-(phenylmethyl)-N-[3-(spiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl)propyl]-2-pyrrolidinecarboxamide, dihydrochloride |
| Anwendung: | Nociceptin receptor antagonist |
| CAS | 1401463-54-4 |
| MW: | 506.5 D |
ab 98,00 €
