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PI-1840
Artikelnummer: TGM-T6941-100mg
Description: PI-1840(IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L). Target: PARP, Proteasome. Smiles: CCCc1ccc(OCC(=O)N(Cc2nc(no2)-c2cccnc2)C(C)C)cc1. References: Ozcan...
| Schlagworte: | PI 1840 |
| Anwendung: | Proteasome inhibitor |
| CAS | 1401223-22-0 |
| MW: | 394.47 D |
ab 53,00 €
![PI-1840 [Proteasome Inhibitor]](https://www.biomol.com/media/image/1e/3f/3c/AG-CR1-3675-M001_200x200.png "PI-1840 [Proteasome Inhibitor]")
PI-1840 [Proteasome Inhibitor]
Artikelnummer: AG-CR1-3675-M005
Synthetic. Chemical. CAS: 1401223-22-0. Formula: C22H26N4O3. MW: 394.5. Synthetic. Highly potent, selective and rapidly reversible non-covalent proteasome inhibitor. Targets the chymotrypsin-like beta5-subunit of the constitutive 20S proteasome (IC50=27nM), with minimal crossreactivity on the trypsin-like (beta2)...
| Schlagworte: | N-(1-Methylethyl)-2-(4-propylphenoxy)-N-[[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl]-acetamide |
| Anwendung: | Proteasome inhibitor |
| CAS | 1401223-22-0 |
| MW: | 394,5 D |
ab 28,00 €
PI-1840
Artikelnummer: Cay37331-10
PI-1840 is an inhibitor of chymotrypsin-like (CTL) proteasome activity (IC50 = 27 nM). It is selective for the CTL activity over the trypsin-like (TL) and peptidylglutamyl peptide hydrolyzing (PGPH) activities (IC50s = >100 µM for both), as well as for the 20S constitutive proteasome over the immunoproteasome (IC50s...
| Schlagworte: | N-(1-methylethyl)-2-(4-propylphenoxy)-N-[[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl]-acetamide |
| Anwendung: | Chymotrypsin-like proteasome activity inhibitor |
| CAS | 1401223-22-0 |
| MW: | 394.5 D |
ab 81,00 €
