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4µ8C
4µ8C

Artikelnummer: TGM-T6363-100mg

Description: 4µ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor. Target: IRE1. Smiles: Cc1cc(=O)oc2c(C=O)c(O)ccc12. References: Cross BC, et al. Proc Natl Acad Sci U S A. 2012, 109(15), E869-878.
Schlagworte: IRE1 Inhibitor III
CAS 14003-96-4
MW: 204.18 D
ab 43,00 €
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4µ8C
4µ8C

Artikelnummer: Cay22110-5

4µ8C is an inhibitor of inositol requiring enzyme 1 alpha (IRE1alpha), which is a protein located in the endoplasmic reticulum (ER) membrane that has kinase and RNase activities triggered by ER stress. 4µ8C inhibits IRE1alpha splicing of Xbp1 mRNA (IC50 = 6.8 µM) and reduces subsequent gene expression of Erdj4 (IC50...
Schlagworte: IRE1 Inhibitor III, 7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde
CAS 14003-96-4
MW: 204.2 D
ab 50,00 €
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